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KMID : 0352720230470050605
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Journal of Ginseng Research
2023 Volume.47 No. 5 p.605 ~ p.614
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Effect of anti-skin disorders of ginsenosides- A Systematic Review
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Lele Cong
Jinli Ma
Yundong Zhang
Yifa Zhou
Xianling Cong
Miao Hao
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Abstract
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Ginsenosides are bioactive components of Panax ginseng with many functions such as anti-aging, anti-oxidation, anti-inflammatory, anti-fatigue, and anti-tumor. Ginsenosides are categorized into dammarane, oleanene, and ocotillol type tricyclic triterpenoids based on the aglycon structure. Based on the sugar moiety linked to C-3, C-20, and C-6, C-20, dammarane type was divided into protopanaxadiol (PPD) and protopanaxatriol (PPT). The effects of ginsenosides on skin disorders are noteworthy. They play anti-aging roles by enhancing immune function, resisting melanin formation, inhibiting oxidation, and elevating the concentration of collagen and hyaluronic acid. Thus, ginsenosides have previously been widely used to resist skin diseases and aging. This review details the role of ginsenosides in the anti-skin aging process from mechanisms and experimental research.
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KEYWORD
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ginsenosides, anti-skin disorders, skin aging, protopanaxadiol type, protopanaxatriols type
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